P2 receptors are membrane-bound receptors for extracellular nucleotides such as ATP and UTP. induced by ATP and UTP was preferentially mediated by P2Y receptors coupled to Gi3 and G q proteins, which activate PLC1 and PLC3. Subsequently, increased intracellular Ca2+ and activated PKC brought on stimulation of MLC kinase and inhibition of MLC phosphatase. Finally,… Continue reading P2 receptors are membrane-bound receptors for extracellular nucleotides such as ATP