Bone fragments metastases are a common problem of epithelial malignancies, of which breasts, lung and prostate carcinomas are the most common. Keywords: bone fragments, metastasis, tumor, microenvironment, metastatic specific niche market 1. Launch Bone fragments metastases are a regular problem of solid malignancies [1]. The institution of bone fragments metastasis can be a significant trigger… Continue reading Bone fragments metastases are a common problem of epithelial malignancies, of