There is increasing evidence that pregnancy alters the function of drug-metabolizing enzymes and drug transporters in a gestational-stage and tissue-specific manner. this issue (Shuster et al., 2013). Some differences in individual Cyp2d mRNA expression were, however, observed between the two studies, highlighting the challenges of quantifying pregnancy-mediated changes in mice. Interestingly, in the microarray study… Continue reading There is increasing evidence that pregnancy alters the function of drug-metabolizing